Background The relationship between pericardial inflammation and subsequent constriction in tuberculous (TB) pericarditis remains poorly understood. Late gadolinium enhancement (LGE) has shown ...

The natural history of symptomatic severe aortic stenosis (AS) heralds a poor prognosis—a paradigm that rightly drives valve ...

Background Hereditary transthyretin amyloidosis (ATTRv) is a rare multisystem disorder with marked phenotypic heterogeneity.

Background Atrial fibrillation (AF) is a common cause of ischaemic stroke and a major global health burden, but is often ...

Background Out-of-hospital cardiac arrest (OHCA) in children is a rare but devastating event, with an estimated incidence of ...

Background Heart failure (HF) remains associated with high mortality worldwide despite advances in guideline-directed therapy ...

Background Observational studies have reported that sleep is associated with the risk of major depressive disorder (MDD) and cardiovascular diseases (CVDs). However, the causal relationships among ...

Objective We investigated the benefit of Impella, a modern percutaneous mechanical support (pMCS) device, versus former standard intra-aortic balloon pump (IABP) in acute myocardial infarction ...

Cardiovascular disease is the leading cause of premature mortality in the developed world, and hypertension is its most important risk factor. Controlling hypertension is a major focus of public ...

Background Amyloid transthyretin (ATTR) amyloidosis is a rare, life-threatening disease frequently manifesting with cardiomyopathy (ATTR-CM), polyneuropathy (ATTR-PN) or both (ATTR-mixed). We ...

Background Ranolazine is an antianginal drug reported to have hypoglycaemic effects. Objectives To assess the effect of ranolazine versus placebo on glycaemic control for adults with and without ...

Objective Smokeless tobacco use is a public health issue throughout the world, but reviews and analyses of circulatory disease risks associated with smokeless tobacco use may be outdated or incomplete ...